Characteristics | Details |
---|---|
Active Ingredients | Sildenafil 100 mg, Vardenafil 20 mg |
Dosage Forms | Tablets |
Administration Route | Oral |
Mechanism of Action | Inhibits PDE5 enzyme |
Recommended Intake | One tablet 30-60 minutes before activity |
Storage | Keep in a cool, dry place |
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Pharmacokinetics
Silvitra combines two potent ingredients: Sildenafil 100 mg and Vardenafil 20 mg. Both are phosphodiesterase type 5 (PDE5) inhibitors. These compounds are absorbed into the bloodstream after oral administration. Peak plasma concentrations occur within one hour. The bioavailability of sildenafil is about 40%, while vardenafil achieves 15%.
Metabolism occurs primarily in the liver via cytochrome P450 enzymes. Sildenafil is extensively metabolized, and its major circulating metabolite has similar properties. Vardenafil is also heavily metabolized, leading to an active metabolite that has a half-life similar to the parent compound. These metabolites are excreted mainly in the feces and, to a lesser extent, in urine.
The combination in Silvitra offers a rapid onset of action. It enhances erectile function by increasing blood flow to the penis. This effect persists for up to four hours, allowing for flexibility. It’s important to note the impact of high-fat meals, which can delay absorption.
Dosage Information
Silvitra tablets come with Sildenafil 100 mg and Vardenafil 20 mg. This formulation provides a robust option for those seeking reliable effects. Patients should ingest the tablet with water, ideally 30-60 minutes before sexual activity. The timing allows for optimal absorption and effect.
While the recommended dose is one tablet, variations might occur based on individual health conditions and response. It’s crucial not to exceed one dose in a 24-hour period. Adjustments may be necessary for those with renal or hepatic impairments. Professional consultation is advised for personalized recommendations.
Silvitra Contraindications
Certain conditions contraindicate the use of Silvitra. Patients with a history of cardiovascular disorders, such as heart attacks or strokes, should avoid this medication. Those with severe hepatic impairment or end-stage renal disease are also advised against its use.
The use of nitrates or nitric oxide donors, in any form, with Silvitra is contraindicated. This combination could cause a significant drop in blood pressure. Individuals with known hypersensitivity to sildenafil, vardenafil, or any excipients should refrain from usage.
Missed Dose
Silvitra is used as needed. There’s no regimen that requires regular dosing, so the concept of a missed dose is inapplicable. Patients should not double doses to compensate. Instead, they should take the medication as per future requirements.
This approach ensures effective management without compromising safety. It’s designed to allow flexibility and responsiveness to individual circumstances.
Side Effects
Common side effects include headaches, flushing, and nasal congestion. Some patients may experience dizziness or visual disturbances. These symptoms are generally mild and transient.
Severe side effects, while rare, can occur. These include priapism, sudden hearing loss, and severe hypotension. In such cases, immediate medical attention is essential. Monitoring and reporting side effects enhance safety and efficacy.
Purchasing Silvitra Without a Prescription
Acquiring Silvitra without a prescription is not recommended. A medical consultation ensures suitability and safety. Prescriptions reflect a comprehensive assessment of individual health profiles.
Unauthorized purchasing can lead to counterfeit products. These products lack the rigorous testing associated with approved pharmaceuticals. Professional guidance guarantees the authenticity and effectiveness of the medication.